Azido-PEG1-CH2COO-Cl (compound 43a) 是一种 PROTAC linker，属于 alkyl/ether 类。可用于合成 PROTAC BRD4 Degrader-1 (HY-133131)。
| 生物活性 | Azido-PEG1-CH2COO-Cl (compound 43a) is an alkyl/ether-basedPROTAClinker. Azido-PEG1-CH2COO-Cl can be used in the synthesis ofPROTACBRD4 Degrader-1 (HY-133131)[1]. |
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体外研究
(In Vitro) | PROTAC BRD4 Degrader-1 is an efficacious BRD4 degrader with an IC50 of 41.8 nM against BRD4 BD1. PROTAC BRD4 Degrader-1 can effectively degrade BRD4 protein and suppress c-Myc expression[1].
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
