GPi 688 是一种有效且具有口服活性的糖原磷酸化酶 (GPa) 抑制剂,对人肝 GPa、大鼠肝 GPa 和人骨骼肌 GPa 的 IC50 分别为 19 nM、61 nM 和 12 nM。
Cas No. | 918902-32-6 |
化学名 | 2-chloro-N-(1-((R)-2,3-dihydroxypropyl)-2-oxo-1,2,3,4-tetrahydroquinolin-3-yl)-6H-thieno[2,3-b]pyrrole-5-carboxamide |
Canonical SMILES | ClC(S1)=CC2=C1NC(C(NC(C3=O)([H])CC4=CC=CC=C4N3C[C@](O)([H])CO)=O)=C2 |
分子式 | C19H18ClN3O4S |
分子量 | 419.88 |
溶解度 | <41.99mg/ml in DMSO;<10.5mg/ml in ethanol |
储存条件 | Store at -20℃ |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |