Acid-PEG4-C2-Boc 是一种PROTAC linker,属于PEG和Alkyl/ether类,可以用于合成抑制 mTOR 的 PROTAC。
| 生物活性 | Acid-PEG4-C2-Boc is aPEG- andAlkyl/ether-basedPROTAClinkercan be used in the synthesis ofPROTACsfor the inhibition ofmTOR[1]. |
| IC50& Target | |
体外研究 (In Vitro) | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | | Pure form | -20°C | 3 years | | 4°C | 2 years | | In solvent | -80°C | 6 months | | -20°C | 1 month |
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