Boc-bipiperidine-ethynylbenzoic acid 是一种PROTAC linker,属于 alkyl/ether 类。可用于合成 PROTAC 分子 ARD-61。
生物活性 | Boc-bipiperidine-ethynylbenzoic acid is an Alkyl/ether-basedPROTAClinkercan be used in the synthesis of ARD-61[1]. |
IC50& Target[1] | |
体外研究 (In Vitro) | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
|
分子量 | |
性状 | |
Formula | |
CAS 号 | |
运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | 4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |