N-(Amino-PEG5)-N-bis(PEG4-acid) 是一种PEG类PROTAC linker,可用于合成 PROTAC。N-(Amino-PEG5)-N-bis(PEG4-acid) 含有一个带有两个末端羧酸的氨基。
生物活性 | N-(Amino-PEG5)-N-bis(PEG4-acid) is aPEG-basedPROTAClinkerused in the synthesis ofPROTACs. N-(Amino-PEG5)-N-bis(PEG4-acid) contains an amino group with two terminal carboxylic acids[1]. |
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体外研究 (In Vitro) | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |