E4CPG ((RS)-ECPG) 是 I 组/II 组代谢型谷氨酸受体 (mGluR) 拮抗剂。
| Cas No. | 170846-89-6 |
| 别名 | (RS)-ECPG |
| 化学名 | (S)-4-(1-amino-1-carboxypropyl)benzoic acid |
| Canonical SMILES | OC([C@](CC)(C1=CC=C(C(O)=O)C=C1)N)=O |
| 分子式 | C11H13NO4 |
| 分子量 | 223.23 |
| 溶解度 | Soluble to 100 mM in 1.1eq. NaOH |
| 储存条件 | Store at RT |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | E4CPG is a novel group I/group II metabotropic glutamate receptor antagonist, more potent than (RS)-MCPG . References:
[1]. Sekiyama N et al. Structure-activity relationships of new agonists and antagonists of different metabotropic glutamate receptorsubtypes. Br J Pharmacol, 1996 Apr, 117(7):1493-503.
[2]. Bedingfield JS et al. Structure-activity relationships for a series of phenylglycine derivatives acting at metabotropic glutamate receptors (mGluRs). Br J Pharmacol. 1995 Dec;116(8):3323-9. |
