VH032 thiol (VHL ligand 6) 是一种 von Hippel-Lindau 蛋白 (VHL) 配体。VH032 thiol (VHL ligand 6) 通过 linker 与 JQ1 结合从而形成 PROTAC 分子。
| Cas No. | 2098836-54-3 |
| 别名 | VHL ligand 6 |
| 分子式 | C23H30N4O4S2 |
| 分子量 | 490.64 |
| 溶解度 | DMSO : 50 mg/mL (101.91 mM; Need ultrasonic) |
| 储存条件 | 4°C, stored under argon |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | VH032 thiol (VHL ligand 6) is a VHL ligand, which binds to pan-BET inhibitor JQ1 via a linker to form PROTAC[1]. [1]. Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521. |
