MutantIDH1-IN-4(compound434)是一种突变型异柠檬酸脱氢酶1(IDH1)的抑制剂，其对R132H、HT1080和U87R132H细胞中的突变型IDH1的IC50值≤0.5μM。
| Cas No. | 1416270-18-2 |
| Canonical SMILES | N#CC1=C(N2C[C@@H](C3CC3)N(C(CCOC)=O)CC2)N=C(C4CC4)C5=C1CC(C)(C)OC5 |
| 分子式 | C25H34N4O3 |
| 分子量 | 438.56 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Mutant IDH1-IN-4 (compound 434) is an inhibitor of mutant Isocitrate dehydrogenase 1 (IDH 1), with IC50 values of ≤ 0.5 μM for mutant IDH1 in R132H, HT1080 and U87R132H cells[1]. [1]. US20170210749A1. |
