(S)-GNE-140是活性较小的GNE-140的对映体，能够抑制乳酸脱氢酶A(LDHA)。
| Cas No. | 2003234-64-6 |
| Canonical SMILES | O=C1N[C@](C2=CSC=C2)(C3=CC=C(N4CCOCC4)C=C3)CC(O)=C1SC5=CC=CC=C5Cl |
| 分子式 | C25H23ClN2O3S2 |
| 分子量 | 499.04 |
| 溶解度 | DMSO : 14 mg/mL (28.05 mM) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | (S)-GNE-140 is the less active enantiomer of GNE-140 which can inhibit Lactate dehydrogenase A (LDHA). [1]. Purkey HE, et al. Cell Active Hydroxylactam Inhibitors of Human Lactate Dehydrogenase with Oral Bioavailability in Mice. ACS Med Chem Lett. 2016 Aug 26;7(10):896-901. |
