β-NF-JQ1 是一种PROTAC，可募集Aryl Hydrocarbon ReceptorE3 连接酶以靶向蛋白质。β-NF-JQ1 使用 β-NF 作为 AhR 配体针对含溴结构域(BRD)的蛋白质，诱导 AhR 和 BRD 蛋白质相互作用，并显示与蛋白质敲低活性相关的有效抗癌活性。
| 生物活性 | β-NF-JQ1 is aPROTACthat recruitsAryl Hydrocarbon ReceptorE3 ligase to target proteins. β-NF-JQ1 is directed againstbromodomain-containing (BRD)proteins using β-NF as an AhR ligand, induces the interaction of AhR andBRDproteins, and displays effective anticancer activity that correlated with protein knockdown activity[1]. |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
