CRBN-6-5-5-VHL 是一种有效的选择性的基于von Hippel-LindauE3配体的cereblon(CRBN) 降解剂，DC50值为 1.5 nM，而对底物 IKZF1 和 IKZF3 的降解几乎没有影响。
| 生物活性 | CRBN-6-5-5-VHL is a potent and selectivevon Hippel-Lindau-basedcereblon(CRBN) degrader with aDC50value of 1.5 nM. CRBN-6-5-5-VHL has almost no effect on the degradation of the neo-substrates IKZF1 and IKZF3[1]. |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | -20°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
