Bosutinib D8 (SKI-606 D8) 是 Bosutinib 的氘代物。Bosutinib 是Src/Abl的双抑制剂,IC50分别为 1.2 nM 和 1 nM。
生物活性 | Bosutinib D8 (SKI-606 D8) is a deuterium labeled Bosutinib. Bosutinib is a dualSrc/Ablinhibitor withIC50s of 1.2 nM and 1 nM, respectively[1][2]. |
IC50& Target | IC50: 1.2 nM (Src), 1 nM (Abl)[1] |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Powder | -20°C | 3 years | | 4°C | 2 years | In solvent | -80°C | 6 months | | -20°C | 1 month |
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