FGFR3-IN-3 (化合物 40a) 是一种有效的FGFR泛型抑制剂,抑制FGFR1,2,3和4的IC50值分别为 2.1 nM,3.1 nM,4.3 nM 和 74 nM。FGFR3-IN-3 可用于膀胱癌的研究。
生物活性 | FGFR3-IN-3 (compound 40a) is a potent and pan-FGFRinhibitor, withIC50s of 2.1 nM, 3.1 nM, 4.3 nM and 74 nM forFGFR1,2,3, and4, respectively. FGFR3-IN-3 can be used for the research of bladdercancer[1]. |
IC50& Target[1] | FGFR1 2.1 nM (IC50) | FGFR2 3.1 nM (IC50) | FGFR3 4.3 nM (IC50) | FGFR4 74 nM (IC50) |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |