NT219 是一种有效的胰岛素受体底物 1/2 (IRS1/2) 和STAT3的双重抑制剂。IRS1/2 和 STAT3 是受各种癌基因调控的主要信号连接。NT219 影响 IRS1/2 降解并抑制 STAT3 磷酸化。NT219 具有研究癌症疾病的潜力。
| 生物活性 | NT219 is a potent and dual inhibitor ofinsulin receptorsubstrates 1/2 (IRS1/2) andSTAT3. IRS1/2 andSTAT3are major signaling junctions regulated by various oncogenes. NT219 affects IRS1/2 degradation and inhibitsSTAT3phosphorylation. NT219 has the potential for the research ofcancerdiseases[1]. |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
