VRT-1353385 (Antibiotic-202) 是从专利 WO2014100158A1 化合物实施例 202 中提取的一流、肠道限制、口服活性的 FimH 粘附抑制剂。
| Cas No. | 1616113-45-1 |
| 别名 | Antibiotic-202 |
| 化学名 | 1-(2,7-bis(((2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)ethynyl)spiro[fluorene-9,4'-piperidin]-1'-yl)ethanone |
| Canonical SMILES | CC(N1CCC2(C3=C(C4=C2C=C(C#C[C@](O5)([H])[C@](O)([H])[C@](O)([H])[C@@](O)([H])[C@@]5([H])CO)C=C4)C=CC(C#C[C@](O6)([H])[C@](O)([H])[C@](O)([H])[C@@](O)([H])[C@@]6([H])CO)=C3)CC1)=O |
| 分子式 | C35H39NO11 |
| 分子量 | 649.68 |
| 溶解度 | ≥ 20.2mg/mL in DMSO |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Sibofimloc (Antibiotic-202) is an antibiotic compound, for treating bacterial infections. References:
[1]. Ramtohul, Yeeman K, et al. Preparation of mannose derivatives via coupling and click cycloaddition reactions for treating bacterial infections. From PCT Int. Appl. (2014), WO 2014100158 A1 20140626. |
