(Pro3)GIP,human

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(Pro3)GIP,human

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

299898-52-5

(Pro3) Gastric Inhibitory Peptide, human

(Pro3) GIP, human ((Pro3) Gastric Inhibitory Peptide, human) 是一种有效、稳定和特异性的人 GIP 受体完全激动剂。(Pro3) GIP, human 对人 GIPR 具有高结合亲和力，K_i/ K_d值为 0.90 nM。(Pro3) GIP, human可用于肥胖相关糖尿病的研究。

生物活性	(Pro3) GIP, human ((Pro3)Gastric Inhibitory Peptide, human) is an efficacious, stable and specifichuman GIP receptor (hGIPR)full agonist. (Pro3) GIP, human has high binding affinity for human GIPR with K_i/ K_dvalues of 0.90 nM. (Pro3) GIP, human can be used for the research of obesity-related diabetes^[1]^[2].
IC₅₀& Target	EC50: 0.026 nM (hGIPR)^[2] Ki/Kd: 0.90 nM (hGIPR); 1.1 nM (Rat GIPR); 0.72 nM (Mouse GIPR)^[2]
体外研究 (In Vitro)	(Pro3) GIP, human induces cAMP accumulation with an EC₅₀value of 0.026 nM^[2]. (Pro3) GIP, human has high binding affinity for human GIPR, Rat GIPR and Mouse GIPR with K_i/ K_dvalues of 0.90 nM, 1.1 nM and 0.72 nM, respectively^[2].
体内研究 (In Vivo)	(Pro3) GIP, human has comparatively weak partial agonist effect in rodent models^[2].
分子量	4951.53
Formula	C₂₂₆H₃₃₈N₆₀O₆₄S
CAS 号	299898-52-5
Sequence Shortening	YAPGTFISDYSIAMDKIHQQDFVNWLLAQKGKKNDWKHNITQ
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.