CAS NO: | 220757-88-0 |
生物活性 | tCFA15 is a trimethyl cyclohexenonic long chain fatty alcohol containing 15 carbon atoms on the side chain, promotes the differentiation of neurons, and may regulatesNotchsignaling. | ||||||||||||||||
IC50& Target | Notch1[1] | ||||||||||||||||
体外研究 (In Vitro) | tCFA15 (10 nM-1 μM) dose-dependently affects the differentiation of neural stem cell-derived neurospheres by promoting neurons at the expense of astrocytes, and such effect is via Notch1. tCFA15 (1 μM) specifically decreases the level of Notch1 mRNA in spheres, and such an effect is also observed in decreases Notch1 expression in neuronal and glial cell cultures[1]. tCFA15 stimulates arginine vasopressin secretion in nerve terminals of the neurohypophysis[2]. | ||||||||||||||||
分子量 | 364.60 | ||||||||||||||||
性状 | Oil | ||||||||||||||||
Formula | C24H44O2 | ||||||||||||||||
CAS 号 | 220757-88-0 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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溶解性数据 | In Vitro: DMSO : 130 mg/mL(356.56 mM;Need ultrasonic) 配制储备液
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以下溶剂前显示的百
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