CAS NO: | 2376914-71-3 |
生物活性 | SMO-IN-3 (compound 12a) is a potentsmoothened (SMO)inhibitor with anIC50value of 34.09 nM forhedgehog(Hh)signaling pathway. SMO-IN-3 has antiproliferative activity against human medulloblastoma cell line Daoy. Anticancer activity[1]. |
IC50& Target | IC50: 34.09 nM (Hh)[1] |
体外研究 (In Vitro) | SMO-IN-3 (compound 12a) has antiproliferative activity against human medulloblastoma cell line Daoy with an IC50of 0.48 μM[1]. |
分子量 | 499.50 |
Formula | C27H25F4N3O2 |
CAS 号 | 2376914-71-3 |
运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
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