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SMO-IN-3
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
SMO-IN-3图片
CAS NO:2376914-71-3

SMO-IN-3 (compound 12a) 是一种有效的smoothened (SMO)抑制剂,对 hedgehog (Hh) 信号通路的IC50为 34.09 nM。SMO-IN-3 对人髓母细胞瘤细胞系 Daoy 有抗增殖作用。具有抗癌活性。
生物活性

SMO-IN-3 (compound 12a) is a potentsmoothened (SMO)inhibitor with anIC50value of 34.09 nM forhedgehog(Hh)signaling pathway. SMO-IN-3 has antiproliferative activity against human medulloblastoma cell line Daoy. Anticancer activity[1].

IC50& Target

IC50: 34.09 nM (Hh)[1]

体外研究
(In Vitro)

SMO-IN-3 (compound 12a) has antiproliferative activity against human medulloblastoma cell line Daoy with an IC50of 0.48 μM[1].

分子量

499.50

Formula

C27H25F4N3O2

CAS 号

2376914-71-3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

 
 
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