Super-TDU(1-31)

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Super-TDU(1-31)

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

Super-TDU (1-31) 是 Super-TDU 的肽片段。Super-TDU (1-31) 是YAP-TEAD复合物的抑制剂。Super-TDU 在胃癌小鼠模型中显示出有效的抗肿瘤活性并抑制肿瘤生长。

生物活性

Super-TDU (1-31) is a peptide fragment of Super-TDU. Super-TDU (1-31) is an inhibitor ofYAP-TEADcomplex. Super-TDU shows potent anti-tumor activity and suppresses tumor growth in gastriccancermouse model^[1]^[2].

体外研究
(In Vitro)

Super-TDU (1-31) (50 nM; 24-72 小时) 可以在很大程度上损害 ACTN1 在 Huh-7 或 LM3 细胞增殖中诱导的细胞活力的增加^[1]。

Cell Viability Assay^[2]

Cell Line:	Liver cancer cell lines of human, including Huh-7, LM3 cells
Concentration:	50 nM
Incubation Time:	24, 48 and 72 h
Result:	Could largely compromise the increased cell viability induced by ACTN1.

分子量

3241.48

Formula

C₁₄₁H₂₁₈N₄₀O₄₈

Sequence Shortening

SVDDHFAKSLGDTWLQIGGSGNPKTANVPQT

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.