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Dihydrotachysterol
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Dihydrotachysterol图片
CAS NO:67-96-9

双氢速甾醇;双氢速变固醇
Dihydrotachysterol 是维生素 D 的一种合成类似物。Dihydrotachysterol 可用于低钙血症(血液中缺乏钙)和甲状旁腺功能减退症(体内缺乏甲状旁腺激素)的研究。
生物活性

Dihydrotachysterol is a synthetic analog of vitamin D. Dihydrotachysterol can be used to for the research of hypocalcemia (lack of calcium in the blood) and hypoparathyroidism (lack of parathyroid hormone in the body)[1][2].

体外研究
(In Vitro)

Dihydrotachysterol is effective in the elevation of serum calcium by stimulating intestinal calcium absorption and mobilizing bone calcium in the absence of parathyroid hormone and of functioning renal tissue[1].
Dihydrotachysterol also increases renal phosphate excretion[1].

体内研究
(In Vivo)

Dihydrotachysterol is a potent synthetic vitamin D analogue that is widely available but more expensive than vitamin D2. It has an onset of action and half-life between those of vitamin D2 and calcitriol. Dihydrotachysterol (initially given at 0.03 to 0.08 mg/kg/day for 2 to 3 days. The final dosages range from 0.004 to 0.04 mg/kg/day) is useful for the treatment of hypoparathyroidism[2].

Animal Model:Animal Model: Five young to middle-aged cats of mixed breeding[2]
Dosage:Initially given at a dosage ranging from 0.03 to 0.08 mg/kg/day for 2 to 3 days. The final dosage ranged from 0.004 to 0.04 mg/kg/day.
Administration:Oral administration
Result:Was useful for the treatment of hypoparathyroidism.
分子量

398.66

Formula

C28H46O

CAS 号

67-96-9

中文名称

双氢速甾醇;双氢速变固醇

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

 
 
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