(R)-DPN (compound 3) 是一种选择性ERβ配体，对于 ERα 和 ERβ 的EC50s 分别为 2.9 和 0.8 nM。(R)-DPN 对 ERβ 比 ERα 显示出非常高的亲和力和效力偏好。(R)-DPN 对 HEC-1 和 U2OS 细胞具有细胞毒性，EC50s 分别为 286、205 nM。
| 生物活性 | R)-DPN (compound 3) is a selectiveERβligand withEC50s of 2.9, 0.8 nM forERαandERβ, respectively. (R)-DPN shows a very high affinity and potency preference forERβoverERα. (R)-DPN shows cytoxicity for HEC-1 and U2OS cells with EC50s of 286, 205 nM, respectively[1]. |
| IC50& Target[1] | ERα 2.9 nM (EC50) | ERβ 0.8 nM (EC50) |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
