Lipoxin B4 (LXB4) methyl ester is a lipid soluble prodrug form of the transcellular metabolite LXB4.
| Cas No. | 97589-07-6 |
| Canonical SMILES | O[C@@H](CCCC(OC)=O)/C=C/C=C\C=C\C=C\[C@@H](O)[C@@H](O)CCCCC |
| 分子式 | C21H34O5 |
| 分子量 | 366.5 |
| 溶解度 | DMF: 50 mg/ml,DMSO: unstable,Ethanol: 50 mg/ml,PBS (pH 7.2): 1 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Lipoxin B4 (LXB4) methyl ester is a lipid soluble prodrug form of the transcellular metabolite LXB4 . LXB4 is a positional isomer of LXA4 produced by the metabolism of 15-HETE or 15-HpETE by human leukocytes. At a concentration of 100 nM, LXB4 inhibits polymorphonuclear leukocyte (PMN) migration stimulated by leukotriene B4 and inhibits LTB4-induced adhesion of PMNs with an IC50 value of 0.3 nM. |
