Furanone C-30

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Furanone C-30

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

247167-54-0

呋喃酮 C-30

Furanone C-30 是一种细菌 (bacterial) 群体感应抑制剂。Furanone C-30 可有效抑制细菌 (如S. mutans及其luxS突变株) 生物膜形成。

生物活性

Furanone C-30 is a quorum sensing inhibitor. Furanone C-30 can effectively inhibitbacterialbiofilm formation byS. mutansand itsluxSmutant strain^[1].

IC₅₀& Target

Bacterial biofilm^[1]

体外研究
(In Vitro)

The difference in the OD590 values is statistically significant at concentrations of 2.0 μg/mL and 4.0 μg/mL compared with the control group. Furanone C-30 (2.0 μg/mL and 4.0 μg/mL) can inhibit biofilm formation byS. mutansand itsluxSmutant strain, although it does not affect the bacterial growth rate itself^[1].

Cell Viability Assay^[1]

Cell Line:	Streptococcusmutans UA159 and itsluxSmutant strain
Concentration:	0.0, 2.0 and 4.0 μg/mL
Incubation Time:	24 hours
Result:	When 2.0 μg/mL was added, the OD590 values forS. mutansand itsluxSmutant strain decreased by 42.7% and 40.8%, respectively. When the concentration was increased to 4.0 μg/mL, a decrease of 61.5% and 60.3%, respectively.

分子量

253.88

Formula

C₅H₂Br₂O₂

CAS 号

247167-54-0

中文名称

呋喃酮 C-30

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.