S07-2005 racemic 是一种有效且具有选择性的醛酮还原酶 1C3 (AKR1C3)抑制剂,对 AKR1C3 和 AKR1C4 的IC50分别为 0.13 μM 和 0.75 μM。S07-2005 racemic 有成为耐药癌症的化疗增强剂的潜力。
| 生物活性 | S07-2005 racemic is a potent and selectivealdo-keto reductase 1C3 (AKR1C3)inhibitor with anIC50value of 0.13 μM and 0.75 μM for AKR1C3 and AKR1C4, respectively. S07-2005 racemic has potential as a chemotherapeutic potentiator forcancer drug resistance[1]. |
| IC50& Target | IC50: 2.88 ± 1.10 μM (AKR1C1), 0.13 ± 0.03 μM (AKR1C3), 0.75 ± 0.32 μM (AKR1C4)[1] |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |