S07-2001 是一种有效且具有选择性的醛酮还原酶 1C3 (AKR1C3)抑制剂,IC50为 2.08 μM。S07-2001 增强了Doxorubicin 抑制癌细胞的活性。S07-2001 有成为耐药癌症的化疗增强剂的潜力。
生物活性 | S07-2001 is a potent and selectivealdo-keto reductase 1C3 (AKR1C3)inhibitor with anIC50value of 2.08 μM. S07-2001 enhances the activity of Doxorubicin againstcancercells. S07-2001 has potential as a chemotherapeutic potentiator forcancer drug resistance[1]. |
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体外研究 (In Vitro) | S07-2001 (50 μM) reduces 27% of MCF-7 cell viability administrated with Doxorubicin[1].
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |