Pyranonigrin A 是从 Penicillium brocae MA-231 中分离和鉴定的。
Cas No. | 773855-65-5 |
Canonical SMILES | C/C=C/C1=C(O)C(C(C(N[C@@H]2O)=O)=C2O1)=O |
分子式 | C10H9NO5 |
分子量 | 223.2 |
溶解度 | DMSO: Soluble,Methanol: Heated |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Pyranonigrin A is a fungal metabolite originally isolated from Aspergillus that has antioxidant activity. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH;) free radicals in a cell-free assay (IC50 = 132.9 μM). Pyranonigrin A (10 μM) suppresses TNF-α-induced expression of vascular cell adhesion molecule 1 (VCAM-1) in human umbilical vein endothelial cells (HUVECs). |