CYP4A11/CYP4F2-IN-1 是一种有效的细胞色素P450 (CYP) 4A11和CYP4F2的双抑制剂，IC50值分别分别为 19 nM 和 17 nM。CYP4A11/CYP4F2-IN-1 具有研究肾脏疾病的潜力。
| 生物活性 | CYP4A11/CYP4F2-IN-1 is a potent dual inhibitor ofcytochrome P450(CYP) 4A11andCYP4F2, withIC50s of 19 nM and 17 nM, respectively. CYP4A11/CYP4F2-IN-1 has potential for the research of renal diseases[1]. |
| IC50& Target[1] | CYP4A11 19 nM (IC50) | CYP4F2 17 nM (IC50) |
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体外研究
(In Vitro) | CYP4A11/CYP4F2-IN-1 (compound 2) inhibits 20-Hydroxyeicosatetraenoic acid (20-HETE) production from arachidonic acid in human renal microsomes, with an IC50of 4.2 nM[1].
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
