ROR agonist-1

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ROR agonist-1

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

2361528-74-5

ROR agonist-1 是一种有效、口服可利用的视黄酸受体相关孤儿受体 C2(RORC2)反向激动剂，抑制人类原始 T_H17 细胞产生 IL-17A 的 pIC₅₀为7.5。

生物活性	RORagonist-1 is a potent and orally bioavailable inverse agonist of theretinoic acid receptor-related orphan receptor C2 (RORC2), inhibition ofIL-17Aproduction from human primary T_H17 cells with a pIC₅₀of 7.5^[1].
IC₅₀& Target	pIC 50: 7.5 (human primary T_H17 cells)^[1]
分子量	526.45
Formula	C₂₁H₂₀F₆N₂O₅S
CAS 号	2361528-74-5
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.