3-O-Methyldopa-d3 hydrate

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3-Methoxy-L-tyrosine-d3 hydrate
3-O-Methyl-L-DOPA-d3 hydrate

3-O-Methyldopa D3 (3-Methoxy-L-tyrosine D3) hydrate 是 3-O-Methyldopa 的氘代物。3-O-Methyldopa (3-Methoxy-L-tyrosine) 是一种由邻苯二酚-O-甲基转移酶 (COMT) 形成的 L-DOPA 代谢物。3-O-Methyldopa 竞争性抑制 L-DOPA和多巴胺 (dopamine) 的药效学。

生物活性	3-O-Methyldopa D3 (3-Methoxy-L-tyrosine D3) hydrate is the deuterium labeled 3-O-Methyldopa. 3-O-Methyldopa (3-Methoxy-L-tyrosine) is a metabolite of L-DOPA which is formed by catechol-O-methyltransferase (COMT). 3-O-Methyldopa competitively inhibits the pharmacodynamics of l-DOPA anddopamine^[1].
体外研究 (In Vitro)	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].
分子量	232.25
Formula	C₁₀H₁₂D₃NO₅
中文名称	3-O-甲基多巴 D3 (水合物)
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.