Herbimycin A 是一种安那霉素抗生素，是 Src 家族激酶 (Src family kinase) 抑制剂。Herbimycin A 与 SH 结构域结合，抑制 p60v-src和 p210BCR-ABL的活性。Herbimycin A 能抑制 Hsp90，阻碍热休克的恢复。Herbimycin A 在体外内皮细胞中表现出抗血管生成活性。
| 生物活性 | Herbimycin A, an ansamycinantibiotic, acts as aSrcfamily kinaseinhibitor. Herbimycin A binds to the SH domain and inhibits the activity of p60v-srcand p210BCR-ABLHerbimycin A inhibitsHsp90and impairs recovery from heat shock. Herbimycin A exhibits antiangiogenic activity in endothelial cells in vitro. |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | | Powder | -20°C | 3 years | | In solvent | -80°C | 6 months | | -20°C | 1 month |
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