Prolgolimab (BCD-100) 是一种人 IgG1 抗PD-1单克隆抗体，含有 Fc 沉默 “LALA” 突变。Prolgolimab 可用于晚期黑色素瘤的研究。
| 生物活性 | Prolgolimab (BCD-100) is a humanIgG1anti-PD-1monoclonal antibody containing the Fc-silencing 'LALA' mutation. Prolgolimab can be used for the research of advanced melanoma[1]. |
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体外研究
(In Vitro) | Prolgolimab is an IgG1 anti-PD-1 mAb that contains the Fc-silencing LALA mutation, which provides an immunopotentiating advantage by abolishing the interaction between the Fcregion of the antibody and FcgR expressed on various immune cells, thus blocking the possible effector functions of the antibody[1].
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| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
