Lecanemab (BAN-2401) 是一种 IgG1 抗可溶性聚合淀粉样蛋白 β (Aβ) 单克隆抗体。Lecanemab 具有跨低聚物、原纤维和不溶原纤维的活性。Lecanemab 可用于阿尔茨海默病的研究。
| 生物活性 | Lecanemab (BAN-2401) is anIgG1anti-soluble aggregated amyloid beta (Aβ) monoclonal antibody. Lecanemab shows activity across oligomers, protofibrils and insoluble fibrils. Lecanemab can be used for the research of Alzheimer's Disease[1]. |
体外研究
(In Vitro) | Lecanemab (0.01-10000 ng/mL) 与大小原纤维结合的 IC50值均为 0.8 nM[1]。Lecanemab 对 Aβ 单体的 Kd值为 2.3 μM[1]。Lecanemab 分别与大小原纤维结合的 KD1值分别为 0.97 和 0.16 nM[1]。
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| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
