Gremubamab

立即咨询

Gremubamab

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

1800381-36-5

MEDI3902

Gremubamab (MEDI3902) 是一种人源化 IgG1 kappa 抗PcrV/Psl单克隆抗体。Gremubamab 结合 PA PcrV 蛋白和 Psl 胞外多糖 Gremubamab 具有研究铜绿假单胞菌感染的潜力。

生物活性

Gremubamab (MEDI3902) is a humanizedIgG1kappa anti-PcrV/Pslmonoclonal antibody. Gremubamab binds to the PA PcrV protein and Psl exopolysaccharide. Gremubamab has the potential for the research ofpseudomonas aeruginosainfections^[1]^[2].

体内研究
(In Vivo)

Gremubamab (1, 5, 15 mg/kg; i.v.; at 1 h postinfection) 改善兔急性肺炎模型的生存结果^[2]。

Animal Model:	Rabbits (acute pneumonia model)^[2]
Dosage:	1, 5, 15 mg/kg
Administration:	I.v.; at 1 h postinfection
Result:	Improved survival outcomes in a dose-dependent manner in a rabbit acute pneumonia model.

CAS 号

1800381-36-5

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.