Cimicifugoside

立即咨询

Cimicifugoside

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

66176-93-0

Cimicifugoside 是一种从升麻单胞菌Cimicifuga simplex中提取的三萜类化合物，是一种新型特异性核苷转运 (nucleoside transport) 抑制剂，协同增强甲氨蝶呤细胞毒性作用。Cimicifugoside 具有免疫抑制活性，其优先针对 B 细胞功能，需要较大剂量来抑制 T 细胞功能。

生物活性	Cimicifugoside, a triterpenoid isolated fromCimicifuga simplex, is a novel specificnucleoside transportinhibitor that displays synergistic potentiation of methotrexate cytotoxicity^[1]. Cimicifugoside shows immunosuppressive activity, which is preferentially directed toward B-cell function with larger doses being required for suppression of T-cell function^[2].
IC₅₀& Target	Nucleoside transport^[1]
分子量	674.82
Formula	C₃₇H₅₄O₁₁
CAS 号	66176-93-0
结构分类	Terpenoids Triterpenes
来源	Plants Ranunculaceae Cimicifuga foetidaLinn.
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.