CI 972 anhydrous 是一会有效的，具有口服活性的，竞争性的嘌呤核苷磷酸化酶(PNP)(Ki=0.83 μM) 抑制剂，正在开发作为 T 细胞选择性免疫抑制剂。
| 生物活性 | CI 972 anhydrous is a potent, orally active, and competitive inhibitor ofpurine nucleoside phosphorylase (PNP)(Ki=0.83 μM) under development as a T cell-selective immunosuppressive agent[1][2]. |
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体内研究
(In Vivo) | CI 972 anhydrous (5-150 mg/kg; p.o.) produces dose-dependent elevation of plasma inosine one hour after administration to rats[1].
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
