Nrf2 activator-2 (compound O15) 是一种蛇床子素衍生物，一种有效的Nrf2激动剂，在 293 T 细胞中的EC50为 2.9 μM。Nrf2 activator-2有效抑制 Keap1 和 Nrf2 的相互作用，从而显示出对 Nrf2 的激活作用。Nrf2 activator-2 显示细胞中泛素化 Nrf2 水平显着降低。
| 生物活性 | Nrf2 activator-2 (compound O15), a Osthole derivative, is a potentNrf2agonist with anEC50of 2.9 μM in 293 T cells. Nrf2 activator-2 effectively inhibits the interaction between Keap1 and Nrf2, thus showing the activation effect on Nrf2. Nrf2 activator-2 shows a marked decrease in the level of ubiquitinated Nrf2 in cells[1]. |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
