Tamtuvetmab

立即咨询

Tamtuvetmab

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

1608122-71-9

AT-005
AT005

Tamtuvetmab (AT-005) 是一种抗CD52的犬用金色单抗。Tamtuvetmab 可增加无进展生存期 (PFS)，对患有稚嫩 T 细胞淋巴瘤 (LSA) 犬表现出疗效。Tamtuvetmab 已被兽医批准。

生物活性

Tamtuvetmab (AT-005) is a caninised blontuvetmab againstCD52. Tamtuvetmab increases progression-free survival (PFS), exhibits in vivo efficacy in dogs with naive T-cell lymphoma (LSA). Tamtuvetmab has been approved by veterinary^[1]^[2].

IC₅₀& Target

CD52^[1]

体内研究
(In Vivo)

Tamtuvetmab (5 mg/mL, 7.5-30 mL; i.v.; 15-30 min) has in vivo efficacy in dogs with naive T-cell lymphoma (LSA), but resulting in vomiting, weight loss, diarrhoea, lethargy, decreased appetite and anorexia^[1].

Animal Model:	T-cell LSA Model in Dog^[1]
Dosage:	5 mg/mL, 7.5-30 mL; Dogs weighing for 2-15 kg received 7.5 mL, for 15.1-30 kg received 15 mL, for 30.1-45 kg received 22.5 mL, for 45.1-60 kg received 30 mL
Administration:	Intravenous injection; 15-30 min
Result:	Showed in vivo efficacy with severe side effect.

CAS 号

1608122-71-9

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.