CAS NO: | 58579-51-4 |
包装 | 价格(元) |
10mM (in 1mL DMSO) | 询价 |
10mg | 询价 |
50mg | 询价 |
Cas No. | 58579-51-4 |
别名 | 盐酸阿那格雷; BL4162A |
化学名 | 6,7-dichloro-5,10-dihydro-3H-imidazo[2,1-b]quinazolin-2-one;hydrochloride |
Canonical SMILES | C1C2=C(C=CC(=C2Cl)Cl)NC3=NC(=O)CN31.Cl |
分子式 | C10H8Cl3N3O |
分子量 | 292.55 |
溶解度 | ≥ 4.9 mg/mL in DMSO,<2.26 mg/mL in EtOH,<2.38 mg/mL in Water |
储存条件 | Store at -20℃ |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Anagrelide is a selective thrombocytopenic agent [1]. Anagrelide is a FDA-approved drug for the treatment of essential thrombocythemia. It is originally identified as a potential inhibitor of platelet aggregation. Anagrelide selectively affects thrombocytes while shows no significant effect on white blood cells, erythrocytes, or coagulation. Anagrelide is revealed to be available in 0.5mg capsules for oral administration. Anagrelide is a potent inotropic agent for dogs with remarkable vasodilatory activity. Additionally, anagrelide can reduce renal blood flow. Furthermore, anagrelide has shown to play roles in other chronic myeloproliferative disorders, such as polycythemia vera, chronic myeloid leukemia and agnogenic myeloid metaplasia. Anagrelide has some side effects involving headache, diarrhea, edema, palpitations, and abdominal pain [1]. References: |
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