Lamprey LH-RH I

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Lamprey LH-RH I

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

102634-23-1

Lamprey LH-RH I 一种促性腺激素释放激素，提高血浆类固醇水平，刺激七鳃鳗排卵，对其他动物模型没有影响。

生物活性

Lamprey LH-RH I is a gonadotropin-releasing hormone, elevates plasma steroid levels and stimulates ovulation in the lamprey without biological activity in other animal models^[1].

体外研究
(In Vitro)

Lamprey LH-RH I has a primary mechanism of transport to the pituitary is simple diffusion from neuronal terminals in the neurohypophysis to the adenohypophysis. An additional route is via secretion into the third ventricle and transport by tanycytes to the adenohypophysis^[2].

体内研究
(In Vivo)

Lamprey LH-RH I (5-200 μg/kg; i.p.; single dose or twice) elevates plasma steroid levels and stimulates lamprey ovulation^[1].

Animal Model:	Female sea-run sea lampreys^[1]
Dosage:	5 μg/kg, 50 μg/kg, 100 μg/kg, 200 μg/kg; dissolved in 0.6% NaCl in distilled water
Administration:	Intraperitoneal injection; single dose or twice; observed for 30 days
Result:	Significantly increased estradiol in a dose-related manner. Resulted 80% of the lampreys ovulation at 200 or 100 μg/kg compared in a doserelated manner.

分子量

1226.34

Formula

C₅₈H₇₉N₁₅O₁₅

CAS 号

102634-23-1

Sequence Shortening

{Glp}-HYSLEWKPG-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.