PAO-Nap 是NAP (naphthalimide) 荧光基团修饰的 PAO。PAO 通过选择性靶向硫氧蛋白还原酶诱导 HL-60 细胞氧化应激介导的凋亡。
| 生物活性 | PAO-Nap is the modified PAO attached a naphthalimide fluorophore using aminocaproic acid as a linker. PAO induces oxidative stress-mediatedapoptosisin HL-60 cells by selectively targetingthioredoxin reductase[1].
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体外研究
(In Vitro) | PAO exhibitsIC50values of 6.2 μM, 9.4 μM, 7.7 μM in HL-60, 7721 and Hela cells (48 h)[1].
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
