Valnemulin HCl 是一种截短侧耳素抗生素，通过结合 50s 核糖体亚基中的肽基转移酶来抑制细菌中的蛋白质合成。
| Cas No. | 133868-46-9 |
| 别名 | 盐酸沃尼妙林 |
| 化学名 | (3aR,4R,5R,7S,8S,9R,9aS,12R)-8-hydroxy-4,7,9,12-tetramethyl-3-oxo-7-vinyldecahydro-4,9a-propanocyclopenta[8]annulen-5-yl 2-((1-((R)-2-amino-3-methylbutanamido)-2-methylpropan-2-yl)thio)acetate hydrochloride |
| Canonical SMILES | O[C@H]([C@](C)(C=C)C1)[C@H](C)[C@]2(CCC3=O)[C@@H]3[C@@]([C@@H]1OC(CSC(C)(C)CNC([C@@H](C(C)C)N)=O)=O)(C)[C@H](C)CC2.Cl |
| 分子式 | C31H52N2O5S.HCl |
| 分子量 | 601.28 |
| 溶解度 | ≥ 25.65mg/mL in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Valnemulin hydrochloride is a pleuromutilin antibiotic which inhibits protein synthesis in bacteria by binding the peptidyl transferase enzyme in the 50s ribosomal subunit. References:
[1]. L. Stipkovits, et al. The efficacy of valnemulin (Econor(R)) in the control of disease caused by experimental infection of calves with Mycoplasma bovis. Research in Veterinary Science, Volume 78, Issue 3, June 2005, Pages 207–215. |
