GQ-16

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GQ-16

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

870554-67-9

GQ-16 是PPARγ的中等亲和力配体，K_i值为 160 nM。GQ-16 有效抑制 Cdk5 介导的 PPARγ 磷酸化。GQ-16 也是 PPARγ 的部分激动剂，可减少脂肪生成。GQ-16 促进胰岛素增敏作用而不会增加体重。

生物活性	GQ-16 is a moderate affinity ligand for the ligand-binding domain (LBD) ofPPARγ, exhibiting aK_iof 160 nM. GQ-16 is an effective inhibitor of Cdk5-mediated phosphorylation ofPPARγ. GQ-16 is a partial agonist ofPPARγwith reduced adipogenic actions. GQ-16 promotesinsulinSensitization without weight gain^[1].
分子量	418.30
Formula	C₁₉H₁₆BrNO₃S
CAS 号	870554-67-9
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.