Fmoc-leucine-13C6,15N

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CAS NO:

1163133-36-5

Fmoc-leucine-13C6,15N 是一种 15N 标记和 13C 标记的 Fmoc-leucine。Fmoc-leucine 是一种选择性的PPARγ调节剂。与罗格列酮相比，Fmoc-leucine 激活 PPARγ 的效力较低，但最大效应相似。Fmoc-leucine 改善正常、饮食诱导的葡萄糖不耐受和糖尿病 db/db 小鼠的胰岛素敏感性。Fmoc-leucine 具有较低的诱导脂肪生成活性。

生物活性	Fmoc-leucine-13C6,15N is a 15N-labeled and 13C-labled Fmoc-leucine. Fmoc-leucine is a selectivePPARγ modulator. Fmoc-leucine activatesPPARγwith a lower potency but a similar maximal efficacy than rosiglitazone. Fmoc-leucine improvesinsulinsensitivity
体外研究 (In Vitro)	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[75].
分子量	360.36
Formula	C₁₅¹³C₆H₂₃¹⁵NO₄
CAS 号	1163133-36-5
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.