Topoisomerase IV inhibitor 2 (compound 7d) 是一种有效的DNA 拓扑异构酶 IV (TOPO IV)抑制剂,对 TOPO IV 和 DNA 促旋酶的IC50分别为 0.23 μM 和 0.43 μM。Topoisomerase IV inhibitor 2 具有抗菌活性,对金黄色葡萄球菌 Nerman 菌株 (Staphylococcus aureus Newman) 和 大肠杆菌 ATCC8739 的 MIC 分别为 0.972 μM 和 0.608 μM。
生物活性 | TopoisomeraseIV inhibitor 2 (compound 7d) is a potentDNAtopoisomeraseIV (TOPO IV)inhibitor withIC50s of 0.23 μM and 0.43 μM for TOPO IV and DNA gyrase, respectively.TopoisomeraseIV inhibitor 2 has anti-bacterial activity, with MICs of 0.972 μM and 0.608 μM inStaphylococcus aureus NewmanandEscherichia coliATCC8739, respectively[1]. |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |