MRS1334 是一种有效的选择性人腺苷 A3(adenosine A3) 受体拮抗剂，对 hA3、rA1、rA2A的Ki分别为 2.69 nM、>100 nM、>100 nM。MRS1334 阻断 Cl-IB-MECA 的保护作用，导致明显的心动过缓和 ST 段升高。
| 生物活性 | MRS1334 is a potent and selective humanadenosine A3receptorantagonist withKis of 2.69 nM, >100 nM, >100 nM for hA3, rA1, rA2A, respectively. MRS1334 blocks the protective effect of Cl-IB-MECA leading to significant bradycardia and elevated ST segment[1][2]. |
| IC50& Target[1] | hA3 2.69 nM (Ki) | rA1 >100 nM (Ki) | rA2A >100 nM (Ki) |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
