Adenosine receptor inhibitor 2 (compound 14b) 是一种有效的AR(腺苷受体)抑制剂。Adenosine receptor inhibitor 2 对 A1/A2AARs 具有双重亲和性，对 A1- 的亲和性高于对A2AAR 的亲和性。Adenosine receptor inhibitor 2 对A1AR和A2AAR的Ki值分别为 52.2 和 167 nM。
| 生物活性 | Adenosine receptorinhibitor 2 (compound 14b) is a potentAR(adenosine receptor) inhibitor.Adenosine receptorinhibitor 2 shows dual affinity toward A1/A2AARs with higher affinity for the A1- than the A2AAR.Adenosine receptorinhibitor 2 hasKivalues of 52.2 nM for theA1ARand 167 nM for theA2AAR[1]. |
| IC50& Target | A1AR 52.2 ± 8.5 nM (Ki) | A2AR 167 ± 22 nM (Ki) | hA2B >1000 nM (Ki) | Adenosine A3receptor >1000 nM (Ki) |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
