IHCH-3064 是一种靶向腺苷A2A受体和HDAC的双效化合物。IHCH-3064 有效结合到 A2AR (Ki=2.2 nM) ，且选择性抑制 HDAC1 (IC50=80.2 nM)，在体外对肿瘤细胞具有良好的抗增殖活性。IHCH-3064 是一种肿瘤免疫治疗剂。
| 生物活性 | IHCH-3064 is a dual-acting compounds targetingAdenosine A2A ReceptorandHDAC. IHCH-3064 exhibits potent binding to A2AR (Ki=2.2 nM) and selective inhibition ofHDAC1(IC50=80.2 nM), with good antiproliferative activity against tumor cell lines in vitro. IHCH-3064 is a tumor immunotherapeutic agent[1]. |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
