L-threo Lysosphingomyelin (d18:1) (L-threo-Sphingosylphosphorylcholine) 是一种内源性生物活性鞘脂。L-threo Lysosphingomyelin (d18:1) 是一种有效的S1P受体激动剂,对于hS1P1、hS1P3、hS1P2的EC50分别为 19.3、131.8 和 313.3 nM。
生物活性 | L-threo Lysosphingomyelin (d18:1) (L-threo-Sphingosylphosphorylcholine) is an endogenous bioactive sphingolipid. L-threo Lysosphingomyelin (d18:1) is a potentS1P receptoragonist withEC50s of 19.3, 131.8, and 313.3 nM for hS1P1, hS1P3, and hS1P2, respectively[1]. |
IC50& Target[1] | S1PR1 19.3 nM (EC50, human) | S1PR3 131.8 nM (EC50, human) | S1PR2 313.3 nM (EC50, human) |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Powder | -20°C | 3 years | In solvent | -80°C | 6 months | | -20°C | 1 month |
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