MCHr1 antagonist 1

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MCHr1 antagonist 1

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

391610-37-0

MCHR1 antagonist 1 是一种选择性的黑色素浓集激素 1 型受体 (melanin concentrating hormone-1 receptor) 拮抗剂，对人 MCH1 受体的K_b和K_i值分别为 1 nM 和 4 nM，在降低体重方面可能起作用。

生物活性	MCHR1antagonist 1 is a selective antagonist ofmelanin concentrating hormone-1 (MCH1) receptor, with aK_bof 1 nM and aK_iof 4 nM at human MCH1, and may be used to reduce the body mass.
IC₅₀& Target	Kb: 1 nM (Human MCH1)^[1] Ki: 4 nM (Human MCH1)^[1]
体外研究 (In Vitro)	MCHR1 antagonist 1 shows potent activities against melanin concentrating hormone-1 receptor, but less potent against human MCH1, NPY1, NPY5, GALR1, GALR2, GALR3, and rat 5HT2C receptors, with K_is of >50000 nM^[1].
分子量	557.59
Formula	C₂₈H₃₃F₂N₅O₅
CAS 号	391610-37-0
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.