Zagociguat 是可溶性鸟苷酸环化酶的刺激剂。Zagociguat 增加一氧化氮 (NO) 信号传导，导致环磷酸鸟苷产量增加。Zagociguat 具有研究非中枢神经系统 (CNS) 疾病的潜力。
| Cas No. | 2201048-82-8 |
| 分子式 | C16H10F4N6 |
| 分子量 | 362.28 |
| 溶解度 | DMSO : 250 mg/mL (690.07 mM; Need ultrasonic) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Zagociguat is the stimulator of soluble guanylate cyclase. Zagociguat increases nitric oxide (NO) signaling leading to an increase in cyclic guanosine monophosphate production. Zagociguat has the potential for the research of noncentral nervous system (CNS) disorders[1]. [1]. Debra J. Wallace, et al. Accelerated Development of a Scalable Synthesis of CY6463, a CNS-Penetrant sGC Stimulator for the Treatment of Neurodegenerative Diseases. Org Process Res Dev. 2021;25(10):2288-2299. |
